To decrease BRCA1 levels, cells were pretreated with BRCA1 or control siRNA 50 n M 72 h or mock transfected control and assayed for sensitivity to I3C as above discount cialis We found that replacing AОІ42 with AОІ40, which is two amino acids shorter, or using a scrambled sequence consisting of the same 42 amino acids, each resulted in significantly less fibrillization Fig

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